Nowadays, 316L stainless steel (316LSS), titanium and alloys of titanium
are widely used in orthopedic surgery with the purpose of splinting bone.
Materials made of titanium and titanium alloy have a good mechanical
properties and good biocompatibility but they have a high cost. Therefore, in
Vietnam, to reduce the cost of medical services, most of the splints are made of
316L stainless steel. However, 316L stainless steel could be corroded and
limited the ability of biological compatibility in the biological environment. To
improve these problems, 316LSS is generally coated biomaterials such as
hydroxyapatite (Ca10(PO4)6(OH)2, HAp).
HAp has chemical composition and biological activity similar to the
natural bone. HAp could stimulate the bonding between the host bone to
implant materials and make bone healing ability faster. Moreover, HAp also
protects for the metal surfaces against corrosion and prevents the release of
metal ions from the substrates into the environment.
However, pure HAp has been dissolved in the physiological environment
which may lead to the disintegration of the coatings and affects the implant
fixation. These disadvantages could deal with doping some trace elements in
the HAp structure by replacing Ca2+ ions with cations and substituting OHgroup with anions. In addition, the present of trace element such as magnesium,
sodium, strontium, fluorine, zinc has also the role to stimulate the new bone
formation and provides minerals for bone cells to grow. Besides, the problem of
postoperative infection should be concerned. Thus, antibacterial elements such
as copper, silver and zinc are also being studied to incorporated into HAp.
Based on the reasons mentioned above, the research topic of thesis is
chosen as following: “Synthesis and characterizations of trace elements codoped hydroxyapatite coatings on 316L stainless steel application in bone
implaint”
